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Mansoureh Eghbali, Ph.D.
Assistant Professor of Anesthesiology
Office:  BH-940 CHS
Phone:  (310) 794-7808
Fax:  (310) 825-6649
Email:  meghbali@ucla.edu
 

Curriculum Vitae

Research Interest

My main interest is to unravel: 1. The molecular basis of the remodeling of voltage activated K channels in heart during cell function and disease and 2. The cardio-protective mechanism of hormones. I am investigating the role of sex hormones in the remodeling of cardiac KCNE2 (MiRP1) regulatory beta subunits and the molecular events (gene activity, protein expression and signaling cascades) triggering the installation and recovery of functional heart hypertrophy during pregnancy.

Representative Publications

Lu R. , Alioua A. , Kumar Y., Eghbali M., Stefani E.,&Toro L. (2006). MaxiK channel partners: physiological impact. J Physiol 570.1: 65–72.

Tanaka Y., Tang G., Takizawa K., Otsuka K., Eghbali M., Song M., Nishimaru K., Shigenobu K., Koike K., Stefani E. & Toro L (2006). Kv channels contribute to NO- and ANP-induced relaxation of a rat conduit artery. J Pharmacol Exp Ther. 317(1):341-54.

Eghbali M., Wang Y., Toro L. & Stefani E. (2006). Heart Hypertrophy during pregnancy: a better functioning heart? Trends in cardiovascular Medicine. 16(8):285-291.

Ropero A.B., Eghbali M., Toro L.& Stefani E. (2006). Heart Estrogen Receptor Alpha: Distinct Membrane and Nuclear Distribution Patterns and Regulation by Estrogen. J. Mol. Cell Cardiol. 41(3):496-510.

 Cavalli A., Eghbali M., Minosyan T.Y., Stefani E.& Philipson K. (2007). Localization of sarcolemmal proteins to lipid rafts in myocardium. Cell calcium. doi:10.1016/j.ceca.2007.01.003. In this work Cavalli and Eghbali contributed equally.

Minosyan T., Lu R., Eghbali M., Toro L. & Stefani E. (2007). Increased 5-HT contractile response in late pregnant rat myometrium associates with a higher density of 5-HT2A receptors. J Physiol. 581(Pt 1):91-7.

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