James N. Weiss, M.D.
Curriculum Vitae

 
Education

1975

M.D. in Medicine
University of Pennsylvania, Philadelphia, PA

1971

A.B. in Physics
Hamilton College, Clinton, NY

Positions

2001-

Chief
Division of Cardiology

1997-

Professor of Physiology
UCLA School of Medicine

1997-

Director
UCLA Cardiovascular Research Laboratories

1993-

Director of Cardiovascular Research
UCLA Division of Cardiology

1991-

Chizuko Kawata Professor of Cardiology
UCLA Division of Cardiology

1990-1997

Associate Director
UCLA Cardiovascular Research Laboratories

1989-1991

Professor of Medicine
UCLA School of Medicine

1985-1989

Associate Professor of Medicine
UCLA School of Medicine

1981-1985

Director of  Cardiac Electrophysiology
UCLA Medical Center

1981-1985

Assistant Professor of Medicine
UCLA School of Medicine

1981-1981

Fellow in Cardiac Electrophysiology
University of Limburg, Maastricht, The Netherlands

1978-1981

Fellow in Cardiology
UCLA Center for the Health Sciences

1976-1978

Resident in Medicine
Hospital of the University of Pennsylvania

1975-1976

Intern in Medicine
Hospital of the University of Pennsylvania

Honors

1998-2008

NIH Merit Award

1997

Distinguished Scientific Achievement Award, American Heart Association, Greater Los Angeles Affiliate

1987-1991

NIH Research Career Development Award

1983­1986

NIH New Investigator Research Award

1979-1981

NIH Postdoctoral Trainee Award

1974

Alpha Omega Alpha

1969

Phi Beta Kappa

Selected Publications

1. M. Morad, R. Feldman and J.N. Weiss.  1972.  Contractile properties of the single cell layered heart of the "sea potato."  The Mt. Desert. Is. Biol. Lab. Bull. 12:72.

2. J.N. Weiss and M. Morad.  1973.  Electromechanical studies in the single cell layered heart of Boltenia Ovifera.  The Mt. Desert. Is. Biol. Lab. Bull.  13:125-128.

3. J.N. Weiss, L. Scott, Y. Goldman and M. Morad.  1974.  Transmembrane electrical activity in the heart of the "sea potato".  The Mt. Desert. Is. Biol. Lab. Bull. 14:133-137.

4. J.N. Weiss and M. Morad.  1974.  Single cell layered heart: electromechanical properties of the heart of Boltenia Ovifera.  Science 186:750­752.

5. J.N. Weiss, Y. Goldman and M. Morad.  1976.  Electromechanical properties of the single cell­layered heart of the tunicate Boltenia Ovifera (sea potato).  J. Gen. Physiol. 68:503­518.

6. M. Morad, J.N. Weiss and L. Cleeman.  1978.  The inotropic action of adrenalin on cardiac muscle: does it relax or potentiate tension.  Europ. J. Cardiol. 7/suppl.:53­62.

7. M. Morad, C. Sanders and J.N. Weiss.  1981.  The inotropic actions of adrenalin on frog ventricular muscle: relaxing vs. potentiating effects.  J. Physiol. (London) 311:585­604.

8. J. Maylie, M. Morad and J.N. Weiss.  1981.  A study of pacemaker potential in rabbit sinoatrial node: measurement of potassium activity under voltage clamp conditions.  J. Physiol. (London) 311:161­178.

9. J.N. Weiss, W. Cabeen and N. Roberts.  1981.  Nodoventricular accessory atrioventricular connection associated with dual atrioventricular nodal pathways: a case report and review of the literature.  J. Electrocardiol. 14:185­190.

10. J.N. Weiss and K.I. Shine.  1981.  Extracellular K+ accumulation during myocardial ischemia: implications for arrhythmogensis.  J. Molec. Cell. Cardiol. 13:699­704.

11. J.N. Weiss and K.I. Shine.  1982.  Extracellular K+ accumulation during myocardial ischemia in isolated rabbit heart.  Am. J. Physiol. 242:H619­H628.

12. J.N. Weiss and K.I. Shine.  1982.  [K+]o accumulation and electrophysiological alterations during early myocardial ischemia.  Am. J. Physiol. 243:H318­H327.

13. H.J.J. Wellens, P. Brugada, D. Roy, J.N. Weiss and F.W. Bar.  1982.  Effect of isoproterenol on the antegrade refractory period of the accessory pathway in patients with the Wolff­Parkinson­White syndrome.  Am. J. Cardiol. 50:180­184.

14. J.N. Weiss, P. Brugada, D. Roy, F.W.H.M. Bar and H.J.J. Wellens. 1982.  Localization of the accessory pathway in the Wolff­Parkinson­White Syndrome from the ventriculo­atrial conduction time of right ventricular apical extrasystole. P.A.C.E. 6:260­267.

15. W.G. Stevenson and J.N. Weiss.  1982.  An unusual mechanism of initiation of circus movement tachycardia in a patient with concealed Wolff­Parkinson­White Syndrome.  P.A.C.E. 6:702­707.

16. K. Nademanee, B.N. Singh, J.A. Hendrickson, V. Intarachat, B. Lopez, G. Feld, D. Cannom and J.N. Weiss.  1982.  Amiodarone in refractory life threatening arrhythmias: prospective evaluation of 96 patients with a particular reference to the roles of suppression of spontaneous vs. inducible arrhythmias as prognostic indices of long term efficacy.  Ann. Int. Med. 98:577­584.

17. K. Nademanee, B.N. Singh, D. Cannom, J. Hendrickson, J.N. Weiss, G. Feld and W. Stevenson.  1983.  Control of sudden recurrent arrhythmic death: role of amiodarone. Am. Heart J. 106:895­901.

18. J.N. Weiss and W.G. Stevenson.  1984.  A new type of ventriculo­atrial gap phenomenon.  P.A.C.E. 7:46­50.

19. G.K. Feld, K. Nademanee, J.N. Weiss, W. Stevenson and B.N. Singh. 1984.  Electrophysiologic basis for the suppression by amiodarone of orthodromic supraventricular tachycardia complicating preexcitation syndromes.  J. Am. Coll. Cardiol. 3:1298­1307.

20. P. Brugada, D. Roy, J.N. Weiss, W.R.M. Dassen and H.J.J. Wellens.  1984.  Dual A­V nodal pathways and atrial fibrillation.  P.A.C.E. 7:240­247.

21. J.K. Perloff, W.G. Stevenson, N.K. Roberts, W. Cabeen and J.N. Weiss. 1984.  Cardiac involvement in myotonic muscular dystrophy (Steinerts Disease): a prospective study of 25 patients.  Am. J. Cardiol. 54:1074­1081.

22. J.N. Weiss, G. Couper, B. Hiltbrand and K.I. Shine.  1984.  Role of acidosis in early contractile dysfunction during ischemia: evidence from pHo measurements.  Am. J. Physiol. 247:H760­H767.

23. G. Couper, J.N. Weiss, B. Hiltbrand and K.I. Shine.  1984.  Extracellular pH and tension during ischemia in the isolated rabbit heart. Effects of heart rate, temperature, and inotropic interventions.  Am. J. Physiol. 247:H916­H927.

24. J.N. Weiss and B. Hiltbrand.  1985.  Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit ventricle.  J. Clin. Invest. 75:436­447.

25. R. Mitra, J.N. Weiss and M. Morad.  1985.  ATP­dependent K+ channel and its possible blockers.  The Mt. Desert. Is. Biol. Lab. Bull.

26. W.G. Stevenson and J.N. Weiss.  1985.  Torsades de pointes due to N­acetylprocainamide: A complication of procainamide therapy in renal failure. P.A.C.E. 8:528­531.

27. W.G. Stevenson, I. Wiener and J.N. Weiss.  1986.  Contribution of the anode to ventricular excitation during bipolar programmed electrical stimulation.  Am. J. Cardiol. 57:582­586.

28. W.G. Stevenson, I. Wiener and J.N. Weiss.  1986.  Comparison of bipolar and unipolar programmed electrical stimulation for the initiation of ventricular arrhythmias: significance of anodal excitation during bipolar stimulation. Circulation. 73:693­700.

29. J.N. Weiss and K.I. Shine.  1986.  The effect of heart rate on [K+]o accumulation during myocardial ischemia.  Am. J. Physiol. 250:H982­H991.

30. J.N. Weiss and W.G. Stevenson.  1986.  Narrow QRS ventricular tachycardia.  Am. Heart J. 112:843­847.

31. J.N. Weiss, E. Runnman and M. Morad.  1986.  Hydrogen peroxide activates large outward K+ currents in isolated ventricular myocytes from Cavia Bobaya (guinea­pig) and Mus Rattus (rat).  The Mt. Desert Is. Biol. Lab. Bull.

32. R. Rothschild, W.G. Stevenson, T. Klitzner and J.N. Weiss.  1987.  Enhancement of conduction in an accessory pathway by noncaptured premature extrastimuli.  J. Am. Coll. Cardiol. 9:455­458.

33. W.G. Stevenson, I. Weiner, J.N. Weiss and T. Klitzner.  1987.  Limitations of the effect bipolar and unipolar conditioning stimuli for inhibition in the human heart.  Am. Heart J. 114:303­310.

34. J.N. Weiss and S.T. Lamp.  1987.  Glycolysis preferentially inhibits ATP­sensitive K+ channels in isolated guinea pig cardiac myocytes.  Science 238:67­69.

35. W.G. Stevenson, I. Wiener and J.N. Weiss.  1987.  Effect of spatial separation of stimulation sites on ventricular refractoriness during programmed electrical stimulation.  Am. Heart J. 114:303­310.

36. W.G. Stevenson, J.N. Weiss, D. Wohlgelernter and L.A. Yeatman. 1987.  Localization of an area of slow conduction in a ventricular tachycardia circuit by entrainment.  Am. Heart J. 114:1253-1258.

37. W.G. Stevenson, J.N. Weiss, I. Wiener, K. Nademanee, D. Wohlgelernter, L. Yeatman, M. Josephson and T. Klitzner.   1988.  Resetting of ventricular tachycardia by programmed electrical stimulation: Implications for localizing the area of slow conduction.  J. Am. Coll. Cardiol. 11:522-529.

38. G. Feld, K. Nademanee, W. Stevenson, J.N. Weiss, T. Klitzner and B.N. Singh. 1988.  Clinical and electrophysiologic effects of amiodarone in patients with atrial fibrillation or flutter complicating the Wolff­Parkinson­White Syndrome.  Am. Heart J. 115:102-107.

39. W.G. Stevenson, I. Wiener, L. Yeatman, D. Wohlgelernter and J.N. Weiss. 1988.  Complicated atherosclerotic lesions: a potential cause of ischemic ventricular arrhythmias in cardiac arrest survivors who do not have inducible ventricular tachycardia?  Am. Heart J. 116: 1-6.

40. W.G. Stevenson, L.W. Stevenson, J.N. Weiss and J.H. Tillisch.  1988.  Programmed ventricular stimulation in severe heart failure: high short-term risk of sudden death despite noninducibility.  Am. Heart J. 116: 1447-1454.

41. W.G. Stevenson, J.N. Weiss, I. Wiener, S.M. Rivitz, K. Nademanee, T. Klitzner, L. Yeatman and D. Wohlgelernter.  1989.  Fractionated endocardial electrograms are associated with slow conduction in humans: evidence from pace­mapping.  J. Am. Coll. Cardiol. 13: 369-376.

42. J.N. Weiss, S. T. Lamp and K.I. Shine.  1989.  K+ loss during myocardial hypoxia and ischemia: relationship to anion efflux in isolated rabbit ventricle.  Am. J. Physiol. 256: H1165-H1175.

43. J.I. Goldhaber, S. Ji, S.T. Lamp and J.N. Weiss.  1989.  Effects of exogenous free radicals on electromechanical function and metabolism in isolated guinea pig and rabbit ventricle: implications for ischemia and reperfusion injury.  J. Clin. Invest. 83:1800-1809.

44. H.F. Yee, J.N. Weiss and G.A. Langer.  1989.  Neuraminadase selectively enhances the transient (T) calcium current in isolated cardiac myocytes.  Am. J. Physiol. 256:C1267-C1272.

45. W.G. Stevenson, K. Nadamanee, J.N. Weiss, I. Wiener, K. Baron, L.A. Yeatman, and C.T. Sherman.  1989.  Programmed electrical stimulation at potential ventricular reentry circuit sites: comparisons of observations in humans with predictions from computer simulations.  Circulation. 80:793-806.

46. J.N. Weiss and S.T. Lamp.  1989.  Cardiac ATP-sensitive K+ channels: evidence for preferential regulation by glycolysis.  J. Gen. Physiol. 94:911-935.

47. S.J. Denardo, W.G. Stevenson, J.N. Weiss.  1989.  Does heart failure alter the adaptation of right ventricular refractoriness to an abrupt increase in heart rate?  Am. Heart J. 117:585-589.

48. W.G. Stevenson, J.N. Weiss, L.W. Stevenson and J.H. Tillisch.  1990.  Programmed ventricular stimulation in heart failure: facilitation of ventricular tachycardia initiation by procainamide.  J. Electrocardiology. 23:77-83.