Curriculum Vitae

Research Interest

Structure and function of ionic channels in developing heart;  Signal pathway in regulation of cardiac ionic currents.

Representative Publications

Chen F, Ding S, Lee BS, Wetzel GT: Sarcoplasmic reticulum Ca2+ ATPase protein and cell contraction. J Mol Cell Cardiol 2000;32:745-755

Wetzel GT, Ding S, Chen F: Molecular cloning of junctin from human and developing rabbit heart. Molecular Genetics and Metabolism 2000;69:252-258.

Chen F. Muscarinic regulation of cardiac L-type Ca2+ current. Cardiovsac Res. 2000;48:362-364.

Chen F, Spicher K, Jiang M, Birnbaumer L, Wetzel GT. Lack of muscarinic regulation of Ca2+ channels in Gi2a gene knockout mouse heart. Am J Physiol (Heart Circ Physiol) 2001;280: H1989-95.

Ding S, Chen F, Klitzner TS, Wetzel GT. Inhibition of L-type Ca2+ channel current in Xenopus Oocytes by amiodarone. J Investigative Med 2001;49:346-52

Chen F, Shannon K, Ding S, Silva ME, Wetzel GT, Klitzner TS, Krogstad P. HIV-1 glycoprotein 120 inhibits cardiac myocyte contraction. AIDS Research and Human Retroviruses 2002; 18(11):777-784

Chen F, Esmailian F, Sun W, , Sarma JSM, Singh BN, Klitzner TS. Azimilide inhibits outward potassium currents in human atrial myocytes. J Cardiovasc Pharmacol Therapeut 2002;7(4):255-264

Shu X, Cheng K, Patel N, Chen F, Joseph E, Tsai H, Chen J. Na,K-ATPase is essential for embryonic heart development in the zebrafish. Development 2003;130: 6165-6173.

Chen F, Klitzner TS, Weiss JN. Calcium Cycling Regulation in Embryonic Mouse Hearts. Submitted.