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Alan Garfinkel, Ph.D.
Professor of Medicine and Physiological Science
Office:  CHS 57-145
Phone:  (310) 794-7214 (Office)
            (310) 794-3594 (Lab)
            (310) 794-3658 (Lab)
Email: 
agarfinkel@mednet.ucla.edu 

 

Curriculum Vitae

Research Interest

Mathematical modeling of cellular and tissue electrophysiology. Analysis of data from experimental and clinical arrhythmias using techniques of nonlinear dynamics ("chaos theory"). Development of pharmacologic and electrophysiologic interventions to prevent or control arrhythmias.

Representative Publications

A Garfinkel, M.L. Spano, W.L. Ditto and J.N. Weiss. Controlling cardiac chaos. Science 257: 1230-1235, 1992

P Krogstad, C Uittenbogaart, R Dickover, YJ Bryson, S Plaeger and A Garfinkel. Primary HIV infection of infants: the effects of somatic growth on lymphocyte and virus dynamics. Clinical Immunology 92:25-33 (1999)

Z. Qu, F. Xie, and A. Garfinkel. Diffusion-induced vortex filament instability in 3-Dimensional excitable media. Phys. Rev. Lett 83: 2668-2671, 1999

S. Port, L. Demer, R. Jennrich, D. Walter and A. Garfinkel. Systolic blood pressure and mortality. The Lancet 355: 175-80, 2000.

A Garfinkel, YH Kim, O Voroshilovsky, Z Qu, JR Kil, MH Lee, HS Karagueuzian, JN Weiss and PS Chen. Preventing ventricular fibrillation by flattening cardiac restitution. Proc. Nat Acad Sci. 97:6061-6066 (and cover), 2000.

Garfinkel, A., Y. Tintut, D. Petrasek, K. Bostrom and L. L. Demer (2004). Pattern formation by vascular mesenchymal cells. Proc Natl Acad Sci U S A 101(25): 9247-50.

Xie, F., Z. Qu, J. Yang, A. Baher, J. N. Weiss and A. Garfinkel (2004). A simulation study of the effects of cardiac anatomy in ventricular fibrillation. J Clin Invest 113(5): 686-93.

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